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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SPPL2C All Species: 5.45
Human Site: S315 Identified Species: 15
UniProt: Q8IUH8 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IUH8 NP_787078.1 684 74503 S315 Q Y Q R P P H S L W A S L P L
Chimpanzee Pan troglodytes XP_523673 684 74537 S315 Q Y Q R P P H S L W A S L P L
Rhesus Macaque Macaca mulatta XP_001115879 684 74573 G315 Q Y Q N P P H G L W A S L P L
Dog Lupus familis XP_548046 660 70155 G296 L S P R P P A G P R A C P R L
Cat Felis silvestris
Mouse Mus musculus A2A6C4 690 76248 G324 R Y Q W V L P G Q R V S V T W
Rat Rattus norvegicus Q5PQL3 577 63718 C226 I C V F V V M C C F M L V L L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507224 648 71872 A292 A G I C I A L A V V W A V F R
Chicken Gallus gallus Q5F383 596 66378 Y245 F F Y D H L V Y V I I G I F C
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_782326 512 56836 D161 S P E P P E W D Y N M I V I W
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.8 94.4 70.4 N.A. 69.1 41.5 N.A. 33 45.3 N.A. N.A. N.A. N.A. N.A. N.A. 33.3
Protein Similarity: 100 99.1 96.1 78.3 N.A. 80.2 57.5 N.A. 51 60 N.A. N.A. N.A. N.A. N.A. N.A. 47.5
P-Site Identity: 100 100 86.6 33.3 N.A. 20 6.6 N.A. 0 0 N.A. N.A. N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 100 86.6 33.3 N.A. 33.3 20 N.A. 26.6 20 N.A. N.A. N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 12 0 0 0 0 12 12 12 0 0 45 12 0 0 0 % A
% Cys: 0 12 0 12 0 0 0 12 12 0 0 12 0 0 12 % C
% Asp: 0 0 0 12 0 0 0 12 0 0 0 0 0 0 0 % D
% Glu: 0 0 12 0 0 12 0 0 0 0 0 0 0 0 0 % E
% Phe: 12 12 0 12 0 0 0 0 0 12 0 0 0 23 0 % F
% Gly: 0 12 0 0 0 0 0 34 0 0 0 12 0 0 0 % G
% His: 0 0 0 0 12 0 34 0 0 0 0 0 0 0 0 % H
% Ile: 12 0 12 0 12 0 0 0 0 12 12 12 12 12 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 12 0 0 0 0 23 12 0 34 0 0 12 34 12 56 % L
% Met: 0 0 0 0 0 0 12 0 0 0 23 0 0 0 0 % M
% Asn: 0 0 0 12 0 0 0 0 0 12 0 0 0 0 0 % N
% Pro: 0 12 12 12 56 45 12 0 12 0 0 0 12 34 0 % P
% Gln: 34 0 45 0 0 0 0 0 12 0 0 0 0 0 0 % Q
% Arg: 12 0 0 34 0 0 0 0 0 23 0 0 0 12 12 % R
% Ser: 12 12 0 0 0 0 0 23 0 0 0 45 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 12 0 % T
% Val: 0 0 12 0 23 12 12 0 23 12 12 0 45 0 0 % V
% Trp: 0 0 0 12 0 0 12 0 0 34 12 0 0 0 23 % W
% Tyr: 0 45 12 0 0 0 0 12 12 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _